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Drug Interactions With Oxycodone/APAP Several medications can cause dangerous drug interactions with oxycodone/APAP, including ... Alprazolam (Xanax ®, Xanax XR ®) Chlordiazepoxide (Librium ®, Limbitrol ®, Librax® pain.emedtv.com/oxycodone-apap /drug-interactions-with-oxycod one-apap.html
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